Medical Science and Discovery <p><span style="font-family: Arial; font-size: small;"><strong>Medical Science and Discovery</strong> (ISSN: 2148-6832) is an international open access, peer-reviewed scientific research journal that provides rapid evaluation of articles in all disciplines of Medical Sciences.&nbsp;</span></p> en-US (Asghar Rajabzadeh) (Elena Jalba) Mon, 19 Aug 2019 19:04:20 +0000 OJS 60 In the evaluation of tracheobronchial lesions, MDCT virtual bronchoscopy with fiber optic bronchoscopy comparison <p><strong>Objective:&nbsp;</strong>The aim of this study is compare multislice CT VB and FOB to assess tracheobronchial lesions with multislace CT VB.</p> <p><strong>Material and Methods:</strong>&nbsp;In the period between September 2012 and August 2013 found indications for bronchoscopy and the total of 44 patients underwent FOB and FOB MDCT-SB were included in the study to be evaluated. All patients underwent VB and/or FOB. In both methods, tracheobronchial tree were divided into 18 separate segments. FOB virtual bronchoscopic findings as the gold standard method to assess the results were considered. Accordingly, positive and negative predictive values of MDCT for VB, sensitivity, selectivity and specificity values were calculated.</p> <p><strong>Results:</strong>&nbsp;Patient ages 1 and 79 (mean: 53 ± 16) of the patients ranged from 7 (16%) female and 37 (84%) were men. In FOB 16 narrowing, 9 congestion, four external compression, 11 mucosal abnormalities were found and in the VB 12 narrowing, 16 obstruction, 8 external compression detected. None of the 11 mucosal findings in the FOB could not be determined in VB. Patients detect in FOB 25 cases were detected in VB; two patients with lesions on the FOB, although not detected in the VB (false negative). In 14 cases both FOB and endoluminal lesion was detected in the VB. FOB lesions not seen in the VB lesion in 5 cases (false positive). According to these values, sensitivity 92%, specificity 73%, positive predictive value (PPV) of 82%, negative predictive value (NPV) 87%, Accuracy: 84%, respectively.&nbsp;</p> <p><strong>Conclusion:</strong>&nbsp;Both mucosal biopsies should not be made to give details because of disadvantages such as virtual bronchoscopy fob is not an alternative for the moment. However tracheobronchial tumor research, interventional bronchoscopic procedures and biopsy guidance, foreign body aspiration of the initial assessment, tracheal injury is evaluation and treatment planning, obstructive lesions of the distal show, stenosis evaluation of endobronchial abnormalities characterization and postoperative follow-up issues of virtual bronchoscopy, constantly evolving detector technology and software when placed through the right indications for routine use will take time, we believe that the rightful place.</p> Zeyni Unverdi, Resat Kervancioglu, Sena Unverdi, Mehmet Sait Menzilcioglu Copyright (c) 2019 Fri, 30 Aug 2019 00:00:00 +0000 The effect of injury type and location on the prognosis of the patients with open globe injuries <p style="font-weight: 400;"><strong>Objective:&nbsp;</strong>&nbsp;Investigation of the effect of the globe injury site and the globe injury type on the postoperative results in the patients with a relatively softer open globe injury (OGI) was aimed.</p> <p style="font-weight: 400;"><strong>Methods:</strong>&nbsp;Medical records of the patients with OGI due to blunt or penetrating trauma were analyzed retrospectively. The patient cohort was divided into laceration and rupture groups. The location of injury was evaluated in zones (I-II-III). Presence and type of the complication (cataract, retinal detachment, etc.) were evaluated. Final best-corrected visual acuity (BCVA) was evaluated as the primary outcome measure.</p> <p style="font-weight: 400;"><strong>Results:</strong>&nbsp;Seventy eyes of 70 patients with OGI were included in the study. While 58 eyes (82.9%) had lacerations, 12 eyes (17.1%) had ruptures. Among the 52 patients with lacerations for whom there was an available BCVA data, 13 (25%) patients showed no change, 32 (61.5%) showed an increase, and 7 (13.5%) showed a decrease in BCVA. Among the 11 patients with ruptures, 2 (18.2%) patients showed no change and 9 (81.8%) showed an increase in BCVA. A complication was observed in 23 (44.2%) patients with laceration and 4 (33.3%) patients with rupture (p: 0.474). No difference was detected in terms of the complication rate between the patients having a different zone of injury. However, final BCVA was lower in those with Zone III injury in comparison to those with Zone II injury (p: 0.028).</p> <p style="font-weight: 400;"><strong>Conclusion:</strong>&nbsp;Although the injury type was thought to have an effect on the final BCVA of the patients with OGI, no difference was detected between the patients with laceration and rupture. Zone III injuries resulted in lower preoperative BCVA values. However, despite a significant difference between Zone II and III injuries, no significant difference was observed in terms of the final BCVA between the patients with Zone I and those with Zone III injuries.</p> Cezmi Dogan, Burak Mergen, Seda Sert, Gulsah Tezcan, Busenur Gonen, Umit Yasar Guleser, Osman Sevki Arslan Copyright (c) Fri, 30 Aug 2019 00:00:00 +0000 Evaluation and treatment of the eosinophilic lung diseases in 7 patients <p style="font-weight: 400;"><strong>Objective:&nbsp;</strong>Eosinophilic lung diseases (ELD) are a rare group of heterogeneous diseases characterized by the increase of the eosinophilic ratio in the airways and lung parenchyma. We aimed to present and discuss the clinical, radiologic and pathologic features of six patients with eosinophilic lung diseases.</p> <p style="font-weight: 400;"><strong>Conclusion:&nbsp;</strong>Peripheral eosinophilia with pulmonary infiltrates is diagnostic clues of eosinophilic lung diseases. Systemic corticosteroids are provided rapid control not only in symptoms but also radiological and clinical improvement of ELD.</p> Tugce Uzar, Gozde Duyu, Ahmet Dirican, Selda Gunaydin, Nazli Topbasi, Hulya Bayiz, Sevket Özkaya Copyright (c) Fri, 30 Aug 2019 00:00:00 +0000