Comparison of serum glutathione peroxidase levels in healthy controls and patients with oral cavity malignancy

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Şeyda Belli
Halit Demir
Ayşegül Kırankaya


Objective: In this study, we investigated the glutathione peroxidase enzyme activity changes in patients with oral cavity malignancies.

Material and Methods: Twenty-five patients with oral cavity malignancy and 24 healthy individuals were included in the study. There was no statistically significant difference between the groups in terms of age, gender and smoking-alcohol consumption habits.

Results: Glutathione peroxidase activity was found to be significantly lower in the blood of patients with oral cavity malignancies than the control group ( 2,238±0,039,  p: 0,0001).

Conclusion: The level of glutathione peroxidase in the blood can be used as an important biomarker for the prognosis and to guide to the treatment approaches for the patients with oral cavity malignancy.


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Belli, Şeyda ., Demir, H., & Kırankaya, A. . (2019). Comparison of serum glutathione peroxidase levels in healthy controls and patients with oral cavity malignancy. Medical Science and Discovery, 6(4), 84–87. Retrieved from
Research Article


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