Prevalance of Molar Incisor Hypomineralization : Meta Analysis Study
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Abstract
Objective: Molar Incisor Hypomineralization (MIH) is defined as the hypomineralization of one or more first permanent molars, which may often also affect permanent incisors. The prevalence rate of MIH has been reported to vary between 2.5%-40.2% in various populations. This study aimed to reveal the general dimensions of MIH and to determine its prevalence in societies to plan long-term disease control programs.
Material and Methods: The database obtained by reviewing all studies on the relevant subject in English literature was examined and the prevalence was calculated using the random effect model. All studies were assessed in terms of publication bias while examining the heterogeneity and meta-regression by using sensitivity analysis.
Results: A total of 70 studies were included in the study and the prevalence of MIH was calculated to be 11.88% (95% CI 10.2%-12.4%). The sample size explained 99% heterogeneity.
Conclusion: This study has revealed that more strategies are needed for the preservation of dental health in this patient group due to the high prevalence of MIH, and there is a need for further prevalence studies involving isolated populations in different parts of the world.
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Accepted 2020-10-23
Published 2020-10-24
References
Dos Santos MPA, Maia CL. Molar Incisor Hypomineralization: Morphological, aetiological, epidemiological and clinical considerations. INTECH Open Access Publisher. 2012; 22:424-445.
Commission on Oral Health, Research & Epidemiology.A review of the developmental defects of enamel index (DDE Index). Report of an FDI Working Group. Int Dent J. 1992; 42:411-426.
Farah R, Drummond B, Swain M, Williams S. Linking the clinical presentation of molar-incisor hypomineralisation to its mineral density. Int J Paediatr Dent. 2010; 20(5):353-360.
Jedeon K, Loiodice S, Marciano C, Vinel A, Canivenc Lavier MC, Berdal A, Babajko S. Estrogen and bisphenol A affect male rat enamel formation and promote ameloblast proliferation. Endocrinology. 2014; 155(9):3365-3375.
Simmer JP, Papagerakis P, Smith CE, Fisher DC, Rountrey AN, Zheng L, Hu JC.Regulation of dental enamel shape and hardness. J Dent Res. 2010; 89:1024-1038.
Klingberg G. Oral manifestations in 22q11 deletion syndrome. Int J Paediatr Dent. 2002; 12(1):14-23.
Jeremias F, Koruyucu M, Küchler EC, Bayram M, Tuna EB, Deeley K, Pierri RA, Souza JF, Fragelli CM, Paschoal MA, Gencay K, Seymen F, Caminaga RM, dos Santos-Pinto L, Vieira AR. Genes expressed in dental enamel development are associated with molar-incisor hypomineralization. Arch Oral Biol. 2013; 58(10):1434-1442.
Lygidakis NA, Dimou G, Marinou D. Molar-incisorhypomineralisation (MIH). A retrospective clinical study in Greek children. II. Possible medical aetiological factors. Eur Arch Paediatr Dent. 2008; 9:207-217.
Weerheijm KL, Duggal M, Mejàre I, Papagiannoulis L, Koch G, Martens LC, Hallonsten AL. Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: A summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent. 2003; 4:110-113.
Weerheijm KL. Molar incisor hypomineralisation (MIH): clinical presentation, aetiology and management. Dent Update. 2004; 31(1): 9-12.
Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151:264-9. Availalable from: https://doi.org/10.7326/0003-4819-151-4-200908180-00135
Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000; 283:2008–2012. Availalable from: https://doi.org/10.1001/jama.283.15.2008
Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977; 33:159–174.
Mathu-Muju K, Wright JT. Diagnosis and treatment of molar incisor hypomineralization. Compend Contin Educ Dent. 2006; 27:604-610.
Jackson D. A clinical study of non-endemic mottling of enamel. Arch Oral Biol. 1961; 5: 212-223.
Koch G, Hallonsten AL, Ludvigsson N, Hansson BO, Holst A, Ullbro C. Epidemiologic study of idiopathic enamel hypomineralization in permanent teeth of Swedish children. Community Dent Oral Epidemiol. 1987; 15(5): 279285.
Leppäniemi A, Lukinmaa PL, Alaluusua S. Nonfluoride hypomineralizations in the permanent first molars and their impact on the treatment need. Caries Res. 2001; 35(1): 36-40.
Da Costa Silva CM, Jeremias F, De Souza JF, De Cassia Loiola Cordeiro R, Santos-Pinto L, Zuanon ACC. Molar incisor hypomineralization: prevalance ,severity and clinical consequences in Brazilian children. Int J Paediatr Dent. 2010; 20:426-434.
Zhao D, Dong B, Yu D, Ren Q, Sun Y. The prevalence of molar incisor hypomineralization: evidence from 70 studies. Int J Paed Dent. 2018; 28(2):170-179. Availalable from: https://doi.org/10.1111/ipd.12323
Emmatty TB, Eby A, Joseph MJ, Bijimole J, Kavita K, Asif I. The prevalence of molar incisor hypomineralization of school children in and around Muvattupuzha, Kerala. J Indian Soc Pedod Prev Dent. 2020; 38:14-19. Availalable from: https://doi.org/10.4103/JISPPD.JISPPD_152_18
Silva FMF, Zhou Y, Vieira FGF, Carvalho FM, Costa MC, Vieira AR. Defining the prevalence of molar incisor hypomineralization in Brazil. Pesqui Bras Odontopediatria Clín Integr. 2020; 20:e5146. Availalable from: https://doi.org/10.1590/pboci.2020.021
Crombie FA, Manton DJ, Weerheijm KL, Kilpatrick NM. Molar incisor hypomineralization: a survey of members of the Australian and New Zealand Society of Paediatric Dentistry. Aust Dent J. 2008; 53:160-166.
Fagrell T. Molar incisor hypomineralisation morphological and chemical aspects, onset and possible etiological factors. Swedish Dent Jour Supp. 2011; 216(5):11-83.
Yannam SD, Amarlal D, Rekha CV. Prevalence of molar incisor hypomineralization in school children aged 8–12 years in Chennai. J Indian Soc Pedod Prev Dent. 2016; 34: 134–138.
Mishra A, Pandey RK. Molar Incisor Hypomineralization: an epidemiological study with prevalence and etiological factors in Indian pediatric population. Int J Clin Pediatr Dent. 2016; 9: 167–171.