Prevalance of Molar Incisor Hypomineralization : Meta Analysis Study

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Can Özükoç
Beyza Ballı Akgöl
Aslı Patır Münevveroğlu


Objective:  Molar Incisor Hypomineralization (MIH) is defined as the hypomineralization of one or more first permanent molars, which may often also affect permanent incisors. The prevalence rate of MIH has been reported to vary between 2.5%-40.2% in various populations. This study aimed to reveal the general dimensions of MIH and to determine its prevalence in societies to plan long-term disease control programs.

Material and Methods: The database obtained by reviewing all studies on the relevant subject in English literature was examined and the prevalence was calculated using the random effect model. All studies were assessed in terms of publication bias while examining the heterogeneity and meta-regression by using sensitivity analysis.

Results: A total of 70 studies were included in the study and the prevalence of MIH was calculated to be 11.88% (95% CI 10.2%-12.4%). The sample size explained 99% heterogeneity.

Conclusion: This study has revealed that more strategies are needed for the preservation of dental health in this patient group due to the high prevalence of MIH, and there is a need for further prevalence studies involving isolated populations in different parts of the world.


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Özükoç, C., Akgöl, B. B., & Münevveroğlu, A. P. (2020). Prevalance of Molar Incisor Hypomineralization : Meta Analysis Study. Medical Science and Discovery, 7(10), 652-658.
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