The prevalence of Helicobacter pylori and its effect on prognosis of patients with COVID-19 Helicobacter pylori and COVID-19

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Ahmed Bilal Genc
Selcuk Yaylaci
Hamad Dheir
Didar Senocak
Elif Ozozen
Kubilay Issever
Deniz Cekic
Havva Kocayigit
Cengiz Karacaer
Elif Kose
Ahmet Nalbant
Ali Tamer
Mehmet Koroglu
Oguz Karabay


Objective: SARS-CoV-2 RNA positivity in stool in COVID-19 infection has been reported at rates varying between 6-83%. The purpose of this study was to determine the prevalence of H.pylori and investigate whether it determines the disease prognosis in COVID-19 patients.

Methods: This study was conducted on 117 confirmed COVID-19 patients who were hospitalized due to symptomatic pneumonia and tested for stool H.pylori antigen. Stool H. pylori test outcomes, demographic parameters, laboratory findings, and prognostic predictors of disease were recorded. The effect of the presence of H.pylori in patients with COVID-19 was analyzed.

Results: The mean age of 117 included patients was 49.68 ± 14.62 years, 78 (66.7%) had COVID PCR positivity and 32 (27.35%) had H.pylori positivity. There was no statistical difference in demographic data, prognosis, and laboratory parameters between those with and without H.pylori.

Conclusion: H.pylori positivity was detected as 27.35% in patients with COVID-19 infection. However, we could not find the positive or negative effect of H.pylori on the prognosis of COVID-19 disease. In conclusion, according to the results of this study, H. pylori positivity or negativity neither determined the severity of the COVID-19 disease nor the poor prognostic indicators of the disease.


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Genc, A. B., Yaylaci, S., Dheir, H., Senocak, D., Ozozen, E., Issever, K., Cekic, D., Kocayigit, H., Karacaer, C., Kose, E., Nalbant, A., Tamer, A., Koroglu, M., & Karabay, O. (2021). The prevalence of Helicobacter pylori and its effect on prognosis of patients with COVID-19. Medical Science and Discovery, 8(4), 208-212.
Research Article


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