An Opportunistic infection during stay home period in COVID 19 outbreak; Helicobacter Pylori Helicobacter pylori infection during stay home period in COVID 19 outbreak

Main Article Content

Mesut Aydin
Serhat Ozer
Yaren Dirik
Ahmet Cumhur Dulger


Objective: Helicobacter pylori infection is a well-established risk factor for gastric cancer, which is more common in developing countries where poor sanitation and domestic overcrowding are common. We tried to analyze the impact of the pandemic on Helicobacter pylori infection during COVID 19 related curfew and stay-at-home order.

Material and Methods: Between 1-30 June 2020 (during stay-at-home order), a total of 172 dyspeptic patients who underwent upper gastrointestinal system endoscopy at our institution following stay-at-home order during COVID pandemic were included in this study along with a control group covering 192 dyspeptic patients who underwent endoscopy between 1-20 June 2019.

Results: When we analyzed gastric biopsy specimens, those who faced stay-at-home order had similar rates of intestinal metaplasia (22% versus 29%; p=0.15) and atrophic gastritis (24% versus 29%; p= 0.396) compared to recent year's data. On the other hand, the rate of H.pylori infection was higher compared to pre-COVID period (59% vs. 46%, p<0.05).

Conclusion: Domestic overcrowding during COVID 19 related stay-at-home order is a risk factor for H.pylori infection.


Download data is not yet available.

Article Details

How to Cite
Aydin, M., Ozer, S., Dirik, Y., & Dulger, A. C. (2021). An Opportunistic infection during stay home period in COVID 19 outbreak; Helicobacter Pylori. Medical Science and Discovery, 8(4), 271-274.
Research Article


1. Taisheng L. Diagnosis and clinical management of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection: an operational recommendation of Peking Union Medical College Hospital (V2.0), Emerging Microbes & Infections,2020; 9:1, 582-585

2. Coronavirus Disease-19: Quarantine Framework for Travelers Entering Korea Quarantine Management Team, COVID-19 National Emergency Response Center Osong Public Health Res Perspect. 2020 Jun; 11(3): 133–139.

3. Tang S., Tang B., Bragazzi N. Analysis of COVID-19 epidemic traced data and stochastic discrete transmission dynamic model. Sci Sin Math. 2020;50 doi: 10.1360/SSM-2020-0053.

4. He D., Zhao S., Lin Q. The relative transmissibility of asymptomatic COVID-19 infections among close contacts. Int J Infect Dis. 2020;94:145–147.

5. Rahmet GÜNER, İmran HASANOĞLU, Firdevs AKTAŞ. COVID-19: Prevention and control measures in community. Turk J Med Sci. 2020; 50(3): 571–577. Published online 2020 Apr 21. doi: 10.3906/sag-2004-146

6. Wroblewski LE, Peek RM Jr, Wilson KT. Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev. 2010;23(4):713-739. doi:10.1128/CMR.00011-10

7. Pan W, Zhang H, Wang L, Zhu T, Chen B, Fan J. Association between Helicobacter pylori infection and kidney damage in patients with peptic ulcer. Ren Fail. 2019;41(1):1028-1034. doi:10.1080/0886022X.2019.1683029

8. Begum Satici, Emine Gocet-Tekin, M. Engin Deniz, Seydi Ahmet Satici. Adaptation of the Fear of COVID-19 Scale: Its Association with Psychological Distress and Life Satisfaction in Turkey. Int J Ment Health Addict. 2020 May 8 : 1–9. doi: 10.1007/s11469-020-00294-0 [Epub ahead of print]

9. Hooi JKY, Lai WY, Ng WK, Suen MMY, Underwood FE, Tanyingoh D, Malfertheiner P, Graham DY, Wong VWS, Wu JCY, Chan FKL, Sung JJY, Kaplan GG, Ng SC. Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis. Gastroenterology. 2017;153:420–429. [PubMed] [Google Scholar].

10. Smith S, Fowora M, Pellicano R. Infections with Helicobacter pylori and challenges encountered in Africa. World J Gastroenterol. 2019;25(25):3183-3195. doi:10.3748/wjg.v25.i25.3183

11. Suvak B, Dulger AC, Suvak O, Aytemiz E, Kemik O. The prevalence of helicobacter pylori among dyspeptic patients in an earthquake-stricken area. Clinics. 2015;70(1):69-72.

12. Kurokawa M, Nukina M, Nakanishi H, Miki K, Tomita S, Tohdo A. Kansenshogaku Zasshi. 1996;70(9):970-975. doi:10.11150/kansenshogakuzasshi1970.70.970.

13. Yamanaka K, Miyatani H, Yoshida Y, et al. Hemorrhagic gastric and duodenal ulcers after the Great East Japan Earthquake Disaster. World J Gastroenterol. 2013;19(42):7426-7432. doi:10.3748/wjg.v19.i42.7426

14. University of Virginia Health System. COVID-19: exercise may help prevent deadly complication. April 15, 2020. Available from: 2020/04/15/covid-19-exercise-may-help-prevent-deadly-complication/. Accessed April 14, 2020.

15. Malm, C. Exercise Immunology. Sports Med 34, 555–566 (2004).

16. İnci̇, A , Çoban, M , Sarıkaya, M , Maden, Ü . (2017). Prediyaliz kronik böbrek hastalarında kesitsel bir çalışma: Yaşam kalitesi ve etkileyen faktörler. Kocatepe Tıp Dergisi , 18 (4) , 130-135 . DOI: 10.18229/kocatepetip.368668

17. Andréa B. C. Braga, André M. N. Fialho, Maria N. Rodrigues, Dulciene M. M. Queiroz, Andreia M. C. Rocha, Lucia L. B. C. Braga, Helicobacter pylori Colonization Among Children up to 6 Years: Results of a Community-based Study from Northeastern Brazil, Journal of Tropical Pediatrics, Volume 53, Issue 6, December 2007, Pages 393–397,

18. van de Haar, J., Hoes, L.R., Coles, C.E. et al. Caring for patients with cancer in the COVID-19 era. Nat Med 26, 665–671 (2020).

19. Sun, J., Aghemo, A., Forner, A., & Valenti, L. (2020). COVID‐19 and liver disease. Liver International.

20. Zamani, M., et al. "Systematic review with meta‐analysis: the worldwide prevalence of Helicobacter pylori infection." Alimentary pharmacology & therapeutics 47.7 (2018): 868-876.

21. Attila, Tan, et al. "Upper socioeconomic status is associated with lower Helicobacter pylori infection rate among patients undergoing gastroscopy." The Journal of Infection in Developing Countries 14.03 (2020): 298-303.

DB Error: Unknown column 'Array' in 'where clause'