Prevalence of H. Pylori Infection in Non-Cirrhotic Patients with Chronic Delta Hepatitis Helicobacter Pylori Prevelance in Delta Hepatitis

Main Article Content

Hasan Mücahit Özbaş
Ahmet Cumhur Dülger
Elif Tugba Tuncel
İskender Aksoy
Mustafa Yakarışık
Merih Şimşek
Mesut Aydin

Abstract

Objective: The relationship between Hepatitis Delta infection and Helicobacter infection in patients with non-cirrhotic hepatitis B infection was retrospectively investigated.


Material and Methods: Stool samples of 117 patients included with Delta hepatitis infection in the study At total 36 of them were tested for H. Pylori infection. To detect  H. Pylori, stool samples were tested using a commercial stool H. Pylori antigen assay.


Results: Of these, 13 (19%) patients had H. Pylori seropositivity in the Hepatitis B infection group and 23 (48%) patients tested positive for H. Pylori infection in hepatitis delta infection group. There was a statistically significant difference between groups regarding H. Pylori seropositivity by the faecal test (p= 0.001).


Conclusion: This study provides new knowledge on H. Pylori infection and reflects the need for evidence-based and comorbid dieases-oriented guidelines in the field of gastroenterology.

Downloads

Download data is not yet available.

Article Details

How to Cite
Özbaş, H. M. ., Dülger, A. C. ., Tuncel, E. T. ., Aksoy, İskender ., Yakarışık, M. ., Şimşek, M. ., & Aydin, M. (2022). Prevalence of H. Pylori Infection in Non-Cirrhotic Patients with Chronic Delta Hepatitis: Helicobacter Pylori Prevelance in Delta Hepatitis. Medical Science and Discovery, 9(1), 29–33. https://doi.org/10.36472/msd.v9i1.658
Section
Research Article
Received 2021-12-28
Accepted 2022-01-09
Published 2022-01-13

References

Taylor JM. Infection by Hepatitis Delta Virus. Viruses. 2020; 12: 648.

Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, Martel C, et al. The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis. J Hepatol. 2020; 73: 523-532.

Parikh NS, Ahlawat R. Helicobacter pylori (2020). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021. PMID: 30480966 Free Books/Documents.

Kotilea K, Bontems P, Touati E. Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection. Adv Exp Med Biol. 2019; 1149: 17-33.

Genta RM, Turner KO. Sonnenberg A.Aliment Pharmacol Ther. 2017; 46: 322-330.

Mese S, Nergiz S, Tekes S, et al. Seroprevalence of serum HBsAg positivity and hepatitis delta virus infection among blood donors in Southeastern Turkey. Clin Ter. 2014; 165:95.

Bahcecioglu IH, Aygun C, Gozel N, et al. Prevalence of hepatitis delta virus (HDV) infection in chronic hepatitis B patients in eastern Turkey: still a serious problem to consider. J Viral Hepat. 2011; 18: 518–24.

Shen DT, Ji DZ, Chen HY, Goyal H, Pan S, Xu HG. Hepatitis D: not a rare disease anymore: global uptodate for 2017-2018. Gut. 2020; 69: 786-788.

Chen HY, Shen DT, Ji DZ, Han PC, Zhang WM, Ma JF, et al. Prevalence and burden of hepatitis D virus infection in the global population: a systematic review and meta-analysis. Gut. 2019; 68: 512-521.

Yurdaydin C, Toy M. Hepatitis delta virus infection: a large burden after all? J Infect Dis. 2020; 221: 1573-1575.

Miao Z, Zhang S, Ou X, Li S, Ma Z, Wang W, et al. Estimating the global prevalence, disease progression, and clinical outcome of hepatitis delta virus infection. J Infect Dis. 2020; 221: 1677-1687.

Karlıdağ G. Prevalence of hepatitis delta in chronic hepatitis B patients. Klimik Journal. 2019; 32: 281-284. Turkish.

Bal T. High Prevalence of Hepatitis Delta Antibody in Siirt Province. J DU Health Sci Inst. 2021; 11: 45-49.

Bayındır Bilman F, Özdemir M, Baysal B, Güzel Kurtoğlu M. Prevalence of H. Pyloriin gastric biopsy specimen in the southeastern region of Turkey. J Infect Dev Ctries. 2016; 10: 1177-1182.

Hughes SA, Wedemeyer H, Harrison PM. Hepatitis delta virus. Lancet. 2011; 378: 73-85.

Tsega E, Mengesha B, Hansson BG, Lindberg J, Nordenfelt E. Hepatitis A, B, and delta infection in Ethiopia: a serologic survey with demographic data. Am J Epidemiol. 1986; 123: 344-51.

Dulger AC, Suvak B, Gonullu H, Gonullu E, Gultepe B, Aydın İ, Batur A, Karadas S, Olmez Ş. High prevalence of chronic hepatitis D virus infection in Eastern Turkey: urbanization of the disease. Arch Med Sci. 2016; 12: 415-20.

Sagnelli E, Stroffolini T, Ascione A, Bonino F, Chiaramonte M, Colombo M, Craxi A, Giusti G, Manghisi OG, Pastore G, et al. The epidemiology of hepatitis delta infection in Italy. J Hepatol. 1999; 15: 211–215.

Kotilea K, Bontems P, Touati E. Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection. Adv Exp Med Biol. 2019; 1149: 17-33.

Abbas Z, Yakoob J, Usman MW, Shakir T, Hamid S, Jafri W. Effect of Helicobacter pylori and its virulence factors on portal hypertensive gastropathy and interleukin (IL)-8, IL-10, and tumor necrosis factor-alpha levels. Saudi J Gastroenterol. 2014; 20: 120-7.

Meşe S, Ozekinci T, Atmaca S, Arikan E, Akin D. Investigation of anticardiolipin antibodies in chronic hepatitis B infection together with total anti-delta positivity][Article in Turkish. Mikrobiyol Bul. 2008; 42: 483-7.

Suvak B, Dulger AC, Aykaç MC, Gonullu H, Gonullu E. Delta hepatitis-related thyroid disease: a unique phenomenon. Prz Gastroenterol. 2015; 10: 169-72.

Taylor JM. Infection by Hepatitis Delta Virus. Viruses. 2020; 12: 648.

Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, Martel C, et al. The global prevalence of hepatitis D virus infection: Systematic review and meta-analysis. J Hepatol. 2020; 73: 523-532.

Parikh NS, Ahlawat R. Helicobacter pylori (2020). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021. PMID: 30480966 Free Books/Documents.

Kotilea K, Bontems P, Touati E. Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection. Adv Exp Med Biol. 2019; 1149: 17-33.

Genta RM, Turner KO. Sonnenberg A.Aliment Pharmacol Ther. 2017; 46: 322-330.

Mese S, Nergiz S, Tekes S, et al. Seroprevalence of serum HBsAg positivity and hepatitis delta virus infection among blood donors in Southeastern Turkey. Clin Ter. 2014; 165:95.

Bahcecioglu IH, Aygun C, Gozel N, et al. Prevalence of hepatitis delta virus (HDV) infection in chronic hepatitis B patients in eastern Turkey: still a serious problem to consider. J Viral Hepat. 2011; 18: 518–24.

Shen DT, Ji DZ, Chen HY, Goyal H, Pan S, Xu HG. Hepatitis D: not a rare disease anymore: global uptodate for 2017-2018. Gut. 2020; 69: 786-788.

Chen HY, Shen DT, Ji DZ, Han PC, Zhang WM, Ma JF, et al. Prevalence and burden of hepatitis D virus infection in the global population: a systematic review and meta-analysis. Gut. 2019; 68: 512-521.

Yurdaydin C, Toy M. Hepatitis delta virus infection: a large burden after all? J Infect Dis. 2020; 221: 1573-1575.

Miao Z, Zhang S, Ou X, Li S, Ma Z, Wang W, et al. Estimating the global prevalence, disease progression, and clinical outcome of hepatitis delta virus infection. J Infect Dis. 2020; 221: 1677-1687.

Karlıdağ G. Prevalence of hepatitis delta in chronic hepatitis B patients. Klimik Journal. 2019; 32: 281-284. Turkish.

Bal T. High Prevalence of Hepatitis Delta Antibody in Siirt Province. J DU Health Sci Inst. 2021; 11: 45-49.

Bayındır Bilman F, Özdemir M, Baysal B, Güzel Kurtoğlu M. Prevalence of H. Pyloriin gastric biopsy specimen in the southeastern region of Turkey. J Infect Dev Ctries. 2016; 10: 1177-1182.

Hughes SA, Wedemeyer H, Harrison PM. Hepatitis delta virus. Lancet. 2011; 378: 73-85.

Tsega E, Mengesha B, Hansson BG, Lindberg J, Nordenfelt E. Hepatitis A, B, and delta infection in Ethiopia: a serologic survey with demographic data. Am J Epidemiol. 1986; 123: 344-51.

Dulger AC, Suvak B, Gonullu H, Gonullu E, Gultepe B, Aydın İ, Batur A, Karadas S, Olmez Ş. High prevalence of chronic hepatitis D virus infection in Eastern Turkey: urbanization of the disease. Arch Med Sci. 2016; 12: 415-20.

Sagnelli E, Stroffolini T, Ascione A, Bonino F, Chiaramonte M, Colombo M, Craxi A, Giusti G, Manghisi OG, Pastore G, et al. The epidemiology of hepatitis delta infection in Italy. J Hepatol. 1999; 15: 211–215.

Kotilea K, Bontems P, Touati E. Epidemiology, Diagnosis and Risk Factors of Helicobacter pylori Infection. Adv Exp Med Biol. 2019; 1149: 17-33.

Abbas Z, Yakoob J, Usman MW, Shakir T, Hamid S, Jafri W. Effect of Helicobacter pylori and its virulence factors on portal hypertensive gastropathy and interleukin (IL)-8, IL-10, and tumor necrosis factor-alpha levels. Saudi J Gastroenterol. 2014; 20: 120-7.

Meşe S, Ozekinci T, Atmaca S, Arikan E, Akin D. Investigation of anticardiolipin antibodies in chronic hepatitis B infection together with total anti-delta positivity][Article in Turkish. Mikrobiyol Bul. 2008; 42: 483-7.

Suvak B, Dulger AC, Aykaç MC, Gonullu H, Gonullu E. Delta hepatitis-related thyroid disease: a unique phenomenon. Prz Gastroenterol. 2015; 10: 169-72.

Most read articles by the same author(s)

1 2 > >>