Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery
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Published:
Jul 27, 2019
Keywords:
Congenital Heart Surgery Atelectasis Dornase Alpha (Pulmozyme®)
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Abstract
One year old patient followed with tetralogy of fallot (TOF) was admitted to our service for surgical repair. Ventricular septal defect (VSD) was repaired with a Dacron patch. The infundibular muscle was resected to allow for unobstructed flow of blood to the pulmonary valve and the area above the pulmonary valve was opened with a polytetrafluoroethylene (PTFE) patch. The patient was intubated three times bacause of the atelectasis ocurred in the lungs after the surgery. Atelectasis was treated with nebulised dornase alpha. It avoided the recurrence of atelectasis and the patient was discharged.
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Mustafa Zor, Abdullah Ozer, Huseyin Demirtas, Yigit Kilic, Baris Mardin, & Baris Mardin. (2019). Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery. Medical Science and Discovery, 2(4), 275–277. Retrieved from https://medscidiscovery.com/index.php/msd/article/view/71
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Case Reports
References
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Lee A. Fleisher. Anesthesia and uncommon disease. Elsevier Health Sciences, 2012; Sixth Ed. pp (6-7)
Oh AY, Kim YH, Kim BK, Kim HS, Kim CS Unexpected tracheomalacia in Marfan syndrome during general anesthesia for correction of scoliosis. Anesth Analg 2002; 95: 331-2.
Kanter RK, Pollack MM, Wright WW, et al. Treatment of severe tracheobronchomalacia with continuous positive airway pressure (CPAP). Anesthesiology 1982; 57: 54–6.
Shah PL, Scott SF, Knight RA, et al. In vivo effect of rhDNase 1 on sputum in patients with cystic fibrosis. Thorax 1996;51(2):119-25.
Hassan NO, Chess PR. Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates. Pediatrics 2001;108:468.
Toulemiat B, Conoscenti G, Fine J. Recombinant human Dnase in management of lobar atelectasis due to retained secretions. Thorax 1995;50:1319-21.
Felcar JM, Guitti JCS, Marson AC, Cardoso JR. Fisioterapiapré-operatória na prevenção das complicações pulmonares emcirurgia cardíaca pediátrica. Rev Bras Cir Cardiovasc. 2008; 23(3):383-8.
Andrejaitiene J, Sirvinskas E, Bolys R. The influence of cardiopulmonary bypass on respiratory dysfunction in early postoperative period. Medicina (Kaunas). 2004; 40(Suppl1):7-12.
Kavanagh BP. Perioperative atelectasis. Minerva Anestesiol. 2008; 74(6):285-7.
Undern-Sternberg BS, Petak F, Saudan S, Pellegrini M, Erb TO, Habre W. Effect of cardiopulmonary bypass and aortic clamping on functional residual capacity and ventilation distribution in children. J Thorac Cardiovasc Surg. 2007; 134(5): 1193-8.
Nina RVAH, Gama MEA, Santos AM, Nina VJS, Figueiredo NETO JA, Mendes VGG, et al. O escore de risco ajustado para cirurgia em cardiopatias congênitas (RACHS-1) pode ser aplicado em nosso meio? Rev Bras Cir Cardiovasc. 2007; 22(4): 425-31.
Healy, Fiona; D. Hanna, Brian; Zinman, Raezelle Current Respiratory Medicine Reviews, Volume 7, Number 2, April 2011 , pp. 78-86(9 Bentham Science Publishers
Lee A. Fleisher. Anesthesia and uncommon disease. Elsevier Health Sciences, 2012; Sixth Ed. pp (6-7)
Oh AY, Kim YH, Kim BK, Kim HS, Kim CS Unexpected tracheomalacia in Marfan syndrome during general anesthesia for correction of scoliosis. Anesth Analg 2002; 95: 331-2.
Kanter RK, Pollack MM, Wright WW, et al. Treatment of severe tracheobronchomalacia with continuous positive airway pressure (CPAP). Anesthesiology 1982; 57: 54–6.
Shah PL, Scott SF, Knight RA, et al. In vivo effect of rhDNase 1 on sputum in patients with cystic fibrosis. Thorax 1996;51(2):119-25.
Hassan NO, Chess PR. Rescue use of DNase in critical lung atelectasis and mucus retention in premature neonates. Pediatrics 2001;108:468.
Toulemiat B, Conoscenti G, Fine J. Recombinant human Dnase in management of lobar atelectasis due to retained secretions. Thorax 1995;50:1319-21.