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Objective: The study aimed to investigate whether a history of preoperative SARS-CoV-2 infection differs in terms of peroperative complications and prognosis in patients who had undergone gynecological surgery in the last one year compared to patients who did not.
Materials and Methods: This retrospective case-control study included 632 patients who underwent laparotomic, laparoscopic, urogynecological and oncological surgeries for various indications between July 2020 and July 2021. The patients were divided into two groups according to positive and negative SARS-CoV-2 RT-PCR (Real-time Polymerase Chain Reaction) test results performed preoperatively. The two groups were compared in terms of demographic characteristics, the operation performed, the type of anesthesia applied during the operations, the status of blood transfusion, operation and hospitalization times, and intraoperative and postoperative complications.
Results: While 5.5% (n=35) of the patients had positive SARS-CoV-2 RT-PCR test results in the preoperative period (group 1), 94.5% (n=597) had negative SARS-CoV-2 RT-PCR test results preoperatively. The following parameters, including age, body mass index (BMI), gravida, parity, number of smokers, and number of patients with the comorbid disease, were similar between the two groups. Moreover, no difference was detected in terms of mean hospitalization time, mean operative time, and the number of patients with intraoperative-postoperative complications between the two groups. However, there was a significant difference between the groups in terms of blood product transfusion requirement [0 patients (0%) vs. 55 patients (9.2%) (p=0.05)].
Conclusion: History of SARS-CoV-2 infection in gynecological surgery does not affect intraoperative and postoperative complications except blood product transfusion requirement.
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American College of Surgeons Facts Sheet, COVID-19: Elective Case Triage Guidelines for Surgical Care, https://www.facs.org/COVID-19/clinical-guidance/review-committee. Accessed Mar 24, 2020.
General Directorate of Public Health of the Ministry of Health. "COVID-19 Pandemisinde Sağlık Kurumlarında Çalışma Rehberi ve Enfeksiyon Kontrol Önlemleri." https://covid19.saglik.gov.tr/TR-66532/saglik-kurumlarinda-calisma-rehberi-ve-enfeksiyon-kontrol-onlemleri.html. Accessed March 9, 2021.
Kho RM, Chang OH, Hare A, Schaffer J, et al. Surgical Outcomes in Benign Gynecologic Surgery Patients during the COVID-19 Pandemic (SOCOVID study). J Minim Invasive Gynecol. 2021:S1553-4650(21)00390-3. doi: 10.1016/j.jmig.2021.08.011. DOI: https://doi.org/10.1016/j.jmig.2021.08.011
American College of Surgeons Facts Sheet: Create a Surgical Review Committee for COVID-19-Related Surgical Triage Decision Making. https://www.facs.org/covid-19/clinical-guidance/review-committee 2020. Accessed March 24, 2020.
General Directorate of Public Health of the Ministry of Health, "Covid-19 salgın yönetimi ve çalışma rehberi. https://covid19bilgi. saglik. gov. tr/tr/salgin-yonetimi-ve-calisma-rehberi. html. Accessed Dec 17, 2021.
Kuru B, Kale A, Basol G, et al. Is it safe to perform elective gynaecologic surgery during the two peaks of COVID-19 pandemic? Int J Clin Pract. 2021;75(11):e14816. doi: 10.1111/ijcp.14816. DOI: https://doi.org/10.1111/ijcp.14816
Ayhan A, Oz M, Topfedaisi Ozkan N, et al. Perioperative SARS-CoV-2 infection among women undergoing major gynecologic cancer surgery in the COVID-19 era: A nationwide, cohort study from Turkey. Gynecol Oncol. 2021;160(2):499-505. DOI: https://doi.org/10.1016/j.ygyno.2020.11.014
Oz M, Altıntas MI, Ersak B, Fırat Cuylan Z, Ozdal B, Moraloglu Tekin O. Covid-19 pandemisi sırasında bir pandemi hastanesinde jinekolojik kanser nedeniyle opere olan hastalarda kısa dönem cerrahi sonuçlar: Tek Merkezli Retrospektif Olgu-kontrol çalışması. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2020; 17(2): 368-371. DOI: https://doi.org/10.38136/jgon.733028
Dursun P, Dervisoglu H, Daggez M, et al., Performing gynecologic cancer surgery during the COVID-19 pandemic in Turkey: A multicenter retrospective observational study. Int J Gynaecol Obstet. 2020;151(1):33-38. DOI: https://doi.org/10.1002/ijgo.13296
Akıllı H, Bolankake N, Kuscu UE, Haberal A, & Ayhan A. Covid-19 Pandemisi Öncesi ve Sonrası Uygulanan Jinekolojik Onkolojik Cerrahilerin Kısa Dönem Sonuçlarının Karşılaştırılması. Sağlık ve Toplum, 2021;31(1), 54-59.
European Centre for Disease Prevention and Control (2020). Novel Coronavirus Disease 2019 (COVID-19) Pandemic: Increased transmission in the EU/EEA and the UK-sixth update-12 March 2020. ECDC; 2020.
Coccolini F, Tartaglia D, Puglisi A, et al. SARS-CoV-2 is present in peritoneal fluid in COVID-19 patients. Ann Surg. 2020;272(3):e240-e242.doi:10.1097/SLA.00000 00000 004030. DOI: https://doi.org/10.1097/SLA.0000000000004030
Lu CW, Liu XF, Jia ZF. 2019-nCoV transmission through the ocular surface must not be ignored. Lancet. 2020;395(10224):e39. DOI: https://doi.org/10.1016/S0140-6736(20)30313-5
Englehardt RK, Nowak BM, Seger MV, Duperier FD. Contamination resulting from aerosolized fluid during laparoscopic surgery. JSLS. 2014;18(3):e2014.00361. DOI: https://doi.org/10.4293/JSLS.2014.00361
Chang L, Yan Y, Wang L. Coronavirus Disease 2019: Coronaviruses and Blood Safety. Transfus Med Rev. 2020;34(2):75-80. DOI: https://doi.org/10.1016/j.tmrv.2020.02.003
Chen Y, Chen L, Deng Q et al. The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients. J Med Virol. 2020;92:833-40. DOI: https://doi.org/10.1002/jmv.25825
Jones D, Faluyi D, Hamilton S, et al. A Prospective Study to Identify Rates of SARS-CoV-2 Virus in the Peritoneum and Lower Genital Tract of Patients Having Surgery: An Observational Study. J Minim Invasive Gynecol. 2021;28(9):1633-1636. DOI: https://doi.org/10.1016/j.jmig.2021.02.006
Toptas GR, Unlubilgin E, Kinay T, et al. Perioperative SARS-CoV-2 Infection in Patients Undergoing Elective Surgery in Gynecology Clinic: Tertiary Center Experience. Gynecol Obstet Reprod Med 2021, 1-7. DOI: https://doi.org/10.21613/GORM.2021.1206