@article{Tire_Yazar_Erdem_2021, title={Can changes in platelet count, mean platelet volume, and platelet distribution width be used to determine the severity of COVID-19?}, volume={8}, url={https://medscidiscovery.com/index.php/msd/article/view/611}, DOI={10.36472/msd.v8i10.611}, abstractNote={<p><strong>Objective:</strong> We aimed to investigate the relation of platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) with other acute phase reactants in COVID-19 new corona virus.</p> <p><strong>Material and Methods:</strong> Thirty one patients with COVID-19 were included in to study. There were three groups as outpatient (Group 1, OP)(n=6), hospital (Group 2, H)(n=16) and intensive care unit (Group 3, IC)(n=9) in this analytic study.</p> <p><strong>Results:</strong> WBC (White Blood Cell), CRP (C-Reactive Protein) values were significantly different in all groups. PDW values were significantly lower in Group 3 than Group 1, 2. The result of ROC analysis was 10.9 as a cut-off value (Area under the curve, AUC)=0.407)</p> <p><strong>Conclusions:</strong> This study indicates that lower PDW may frequently develop in COVID-19 cases and there is a relation between thrombocytosis and acute phase reactants, that is, the inflammatory response. So we can offer that PDW should be used as a marker of Covid-19 disease severity, but it needs more studies in the future.</p>}, number={10}, journal={Medical Science and Discovery}, author={Tire, Yasin and Yazar, Mehmet Akif and Erdem, Said Sami}, year={2021}, month={Oct.}, pages={581–585} }