@article{Çiftçi_Saraçgil Coşar_Uzunkulaoğlu_2022, title={Serum 25-Hydroxyvitamin D level in Restless Legs Syndrome: A controlled study}, volume={9}, url={https://medscidiscovery.com/index.php/msd/article/view/670}, DOI={10.36472/msd.v9i1.670}, abstractNote={<p><strong>Objective:</strong> We aimed to investigate 25-hydroxyvitamin D (25-OHD) level on a group of restless legs syndrome (RLS) patients.</p> <p><strong>Material and Methods:</strong> Twenty-one RLS patients and fourteen age and gender healthy controls (non RLS) with similar age and gender were included in the study. All patients underwent a physical examination for the neurologic and musculoskeletal system. The 25-OHD level was measured for all participants.  </p> <p><strong>Results:</strong> The 25-hydroxyvitamin D levels were higher in the RLS patient group (20.06±8.79 ng/ml) than in the healthy control group (14.75±4.67 ng/ml). In the healthy control group ‘’without the RLS syndrome’’, 25-hydroxyvitamin D levels were below the normal range (<20 ng/ml). However, there were no statistical differences in terms of vitamin D level between the RLS and Control groups (p>0.05).</p> <p><strong>Conclusion:</strong> In this study, due to the absence of RLS syndrome in the control group despite low 25-hydroxyvitamin D levels (<20 ng/ml), a relationship could not be established between 25-hydroxyvitamin D levels and RLS syndrome. The cause of RLS syndrome does not seem to depend on a single parameter such as 25-OHD level.</p>}, number={1}, journal={Medical Science and Discovery}, author={Çiftçi, Betül and Saraçgil Coşar, Sacide Nur and Uzunkulaoğlu, Aslıhan}, year={2022}, month={Jan.}, pages={34–38} }