Serum AMH levels are not associated with adverse perinatal outcomes in women undergoing IVF treatment due to diminished ovarian reserve Association between AMH and perinatal outcomes

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Coşkun Şimşir
Tolga Ecemiş
Aynur Adeviye Erşahin
Gürhan Güney
Buğra Çoşkun
Bora Çoşkun
Sevtap Handemir Kılıç


Objective: Anti-Mullerian hormone (AMH) is used as a biomarker for the estimation of fertility related parameters such as quality and quantity of oocytes in in vitro fertilization (IVF) procedures. High oocyte quality may also be associated with healthy trophoblastic invasion and lower complication rates during pregnancy. The aim of this study is to evaluate the relationship between AMH values and perinatal complications in infertile women with poor ovarian reserve (POR).

Material and Methods: A total of 68 women undergoing IVF treatment were included in the study. Thirty six of them constituted the study group (POR) and 32 pregnant women constituted the control group (Tubal factor). All women in the study were chosen from patients who have undergone to their first IVF cycle. Serum AMH levels were analyzed with an ELISA kit in all patients.

Results: AMH level was 5.4 times higher in the control group compared to that of the study group (p<0.05). No significant differences were observed between the groups with regard to preterm birth rate, gestational age at birth, birth weight, 1st and 5th minute Apgar scores, and neonatal intensive care unit admission rates (all, p>0.05).

Conclusion: We found that AMH did not predict adverse perinatal outcomes in women with POR.


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Şimşir, C., Ecemiş, T., Erşahin, A. A., Güney, G., Çoşkun, B., Çoşkun, B., & Handemir Kılıç, S. (2019). Serum AMH levels are not associated with adverse perinatal outcomes in women undergoing IVF treatment due to diminished ovarian reserve. Medical Science and Discovery, 6(9), 160-165. Retrieved from
Research Article


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