An Evaluation of Antibiotic Prescribing Practices Among Dentists in Turkey for the Management of Periodontal and Peri-Implant Diseases Antibiotics in periodontal and peri-implant therapy

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Gözde Erimli
Duygu Kılıç


Objective: The utilization of antibiotics alongside surgical and nonsurgical mechanical interventions for the management of periodontal and peri-implant diseases lacks standardization. Hence, this study aims to investigate the antibiotic prescribing practices among dentists in Turkey to elucidate the rationale and timing behind systemic antibiotic usage in the treatment of these ailments.

Materials and Methods: Between May 2021 and October 2022, 312 dentists across Turkey were invited to participate in a cross-sectional survey. A chi-squared test was used to compare categorical variables according to groups. G-power analysis was used to determine the sample size before the study.

Results: The frequency of antibiotic prescriptions during the initial management of periodontitis, peri-implant mucositis, and gingivitis was observed to be lower compared to other procedures. As treatments progressed from nonsurgical to surgical interventions, there was a concurrent rise in the frequency of antibiotic prescriptions. Amoxicillin + clavulanic acid emerged as the most frequently prescribed antibiotic, with the primary reasons for prescription being the mitigation of infection risk and adherence to established literature guidelines.

Conclusions: A discernible upward trend in antibiotic prescription is evident as treatment transitions from nonsurgical to more complex surgical modalities. The findings of our survey offer valuable insights for dentists in selecting appropriate antibiotics for the management of periodontal and peri-implant diseases.


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How to Cite
Erimli, G., & Kılıç, D. (2024). An Evaluation of Antibiotic Prescribing Practices Among Dentists in Turkey for the Management of Periodontal and Peri-Implant Diseases: Antibiotics in periodontal and peri-implant therapy. Medical Science and Discovery, 11(4), 103–111.
Research Article
Received 2024-01-30
Accepted 2024-03-05
Published 2024-04-01


Hong DGK, Oh JH. Recent advances in dental implants. 2017;39(1):33.

Howe M-S, Keys W, Richards D. Long-term (10-year) dental implant survival: A systematic review and sensitivity meta-analysis. Journal of dentistry. 2019;84:9-21.

Tonetti MS, Chapple IL, Jepsen S, Sanz M. Primary and secondary prevention of periodontal and peri‐implant diseases: Introduction to, and objectives of the 11th European Workshop on Periodontology consensus conference. Journal of clinical periodontology. 2015;42:S1-S4.

Lang NP, Berglundh T, Periodontology WGotSEWo. Periimplant diseases: where are we now?–Consensus of the Seventh European Workshop on Periodontology. Journal of clinical periodontology. 2011;38:178-81.

Slots J, Ting M. Systemic antibiotics in the treatment of periodontal disease. Periodontology 2000. 2002;28(1):106-76.

Mombelli A, Schmid B, Rutar A, Lang NP. Persistence patterns of Porphyromonas gingivalis, Prevotella intermedia/nigrescens, and Actinobacillus actinomycetemcomitans after mechanical therapy of periodontal disease. Journal of periodontology. 2000;71(1):14-21.

Beikler T, Abdeen G, Schnitzer S, Sälzer S, Ehmke B, Heinecke A, et al. Microbiological shifts in intra‐and extraoral habitats following mechanical periodontal therapy. Journal of clinical periodontology. 2004;31(9):777-83.

Kinane DF, Stathopoulou PG, Papapanou PN. Authors' reply: Predictive diagnostic tests in periodontal diseases. Nature Reviews Disease Primers. 2017;3(1):1-.

Seiler JS, Herold RW. The use of systemic antibiotics in the treatment of aggressive periodontal disease. General dentistry. 2005;53(2):155-9; quiz 60, 45.

Herrera D, Alonso B, León R, Roldán S, Sanz M. Antimicrobial therapy in periodontitis: the use of systemic antimicrobials against the subgingival biofilm. Journal of clinical periodontology. 2008;35:45-66.

Heitz-Mayfield LJ, Mombelli A. The therapy of peri-implantitis: a systematic review. International Journal of Oral & Maxillofacial Implants. 2014;29.

Blair FM, Chapple IL. Prescribing for periodontal disease. Primary dental journal. 2014;3(4):38-43.

Genco RJ. Using antimicrobial agents to manage periodontal diseases. The Journal of the American Dental Association. 1991;122(9):30-8.

Haffajee AD, Socransky SS, Gunsolley JC. Systemic anti‐infective periodontal therapy. A systematic review. Annals of Periodontology. 2003;8(1):115-81.

Sanz M, Teughels W, Periodontology GAotEWo. Innovations in non‐surgical periodontal therapy: Consensus Report of the Sixth European Workshop on Periodontology. Journal of clinical periodontology. 2008;35:3-7.

Ong A, Kim J, Loo S, Quaranta A, Rincon A JC. Prescribing trends of systemic antibiotics by periodontists in Australia. Journal of periodontology. 2019;90(9):982-92.

Falkenstein S, Stein JM, Henne K, Conrads G. Trends in antibiotic use and microbial diagnostics in periodontal treatment: comparing surveys of German dentists in a ten-year period. Clinical oral investigations. 2016;20(8):2203-10.

Lang NP. Consensus statements and recommended clinical procedures regarding implant survival and complications. Int J Oral Maxillofac Implants. 2004;19:150-4.

Hallström H, Persson GR, Lindgren S, Olofsson M, Renvert S. Systemic antibiotics and debridement of peri‐implant mucositis. A randomized clinical trial. Journal of clinical periodontology. 2012;39(6):574-81.

Khan A, Sharma D. Management of peri-implant diseases: a survey of Australian periodontists. Dentistry Journal. 2020;8(3):100.

Gomes SC, Corvello P, Romagna R, Müller LH, Angst P, Oppermann RV. How do peri-implant mucositis and gingivitis respond to supragingival biofilm control-an intra-individual longitudinal cohort study. Eur J Oral Implantol. 2015;8(1):65-73.

Salvi GE, Aglietta M, Eick S, Sculean A, Lang NP, Ramseier CA. Reversibility of experimental peri‐implant mucositis compared with experimental gingivitis in humans. Clinical oral implants research. 2012;23(2):182-90.

Walker C, Karpinia K. Rationale for use of antibiotics in periodontics. Journal of periodontology. 2002;73(10):1188-96.

Yiğit U, Karaaslan F, Dikilitaş A, Doğan B. Evaluation of systemic antibiotic usage in the treatment of periodontal diseases among dental professionals in Turkey: Cross-sectional epidemiological study. Balkan Journal of Dental Medicine. 2022;26(2):118-26.

Polymeri A, van der Horst J, Anssari Moin D, Wismeijer D, Loos BG, Laine ML. Non‐surgical peri‐implantitis treatment with or without systemic antibiotics: a randomized controlled clinical trial. Clinical Oral Implants Research. 2022;33(5):548-57.

Papathanasiou E, Finkelman M, Hanley J, Parashis AO. Prevalence, etiology and treatment of peri‐implant mucositis and peri‐implantitis: a survey of periodontists in the United States. Journal of periodontology. 2016;87(5):493-501.

Heitz-Mayfield L, Lang NP. Comparative biology of chronic and aggressive periodontitis vs. peri-implantitis. Periodontology 2000. 2010;53:167-81.

Lindhe J, Berglundh T, Ericsson I, Liljenberg B, Marinello C. Experimental breakdown of peri‐implant and periodontal tissues. A study in the beagle dog. Clinical oral implants research. 1992;3(1):9-16.

Nyman S, Lindhe J, Karring T, Rylander H. New attachment following surgical treatment of human periodontal disease. Journal of clinical periodontology. 1982;9(4):290-6.

Hai JH, Lee C, Kapila YL, Chaffee BW, Armitage GC. Antibiotic prescribing practices in periodontal surgeries with and without bone grafting. Journal of periodontology. 2020;91(4):508-15.

Carcuac O, Derks J, Abrahamsson I, Wennström JL, Petzold M, Berglundh T. Surgical treatment of peri‐implantitis: 3‐year results from a randomized controlled clinical trial. Journal of clinical periodontology. 2017;44(12):1294-303.

Froum SJ, Weinberg MA. An Evaluation of Antibiotic Use in Periodontal and Implant Practices. International Journal of Periodontics & Restorative Dentistry. 2015;35(4).

Sheikh Rezaei S, Litschauer B, Anderle K, Maurer S, Beyers PJ, Reichardt B, et al. Antibiotic prescription after tooth extraction in adults: a retrospective cohort study in Austria. BMC Oral Health. 2022;22(1):1-9.


Dell'Olmo F, Blasi G, Monje A, Mariotti A, Valles C, Pascual A, et al. Periodontists' Trends in the Management of Peri-implant Diseases. Internat