Thyrotoxicosis due to functioning metastatic follicular thyroid cancer

Article Sidebar

Full Text (PDF)
Published: Oct 15, 2016
Keywords:
metastatic follicular thyroid cancer thyrotoxicosis

Main Article Content

Sadiye Altun Tuzcu
Gazi Yasargil Education and Research Hospital, Dept of Nuclear Medicine, Yenisehir, Diyarbakır, Turkey
Faruk Kilinc
Elazıg Education and Research Hospital Dept of Endocrinology, Elazıg, Turkey
Zafer Pekkolay
Dicle University Faculty of Medicine Dept of Endocrinology Diyarbakır, Turkey
Hikmet Soylu
Dicle University Faculty of Medicine Dept of Endocrinology Diyarbakır, Turkey
Alpaslan Kemal Tuzcu
Dicle University Faculty of Medicine Dept of Endocrinology Diyarbakır, Turkey

Abstract

Thyrotoxicosis is a common condition associated with excess circulating thyroid hormones. Rarely, thyrotoxicosis can be developing due to functioning metastatic thyroid carcinoma. Most of patients with functional thyroid cancer metastases have had normal thyroxine (T4) concentrations but high serum triiodothyronine (T3-thyrotoxicosis). Inappropriately supressed TSH levels with normal T4 levels may be helpful to suspect T3 thyrotoxicosis. In this case report we present a case of thyrotoxicosis due to metastatic follicular thyroid cancer with a huge metastatic lesion.

Downloads

Download data is not yet available.

Article Details

How to Cite
Tuzcu, S. A. ., Kilinc, F. ., Pekkolay, Z. ., Soylu, H. ., & Tuzcu, A. K. . (2016). Thyrotoxicosis due to functioning metastatic follicular thyroid cancer. Medical Science and Discovery, 3(10), 339–341. Retrieved from https://medscidiscovery.com/index.php/msd/article/view/177
Issue
Vol. 3 No. 10 (2016): Medical Science and Discovery
Section
Research Article

https://creativecommons.org/licenses/by-nc/4.0/

References

Vaidya B, Pearce SH. Diagnosis and management of thyrotoxicosis. BMJ. 2014 Aug 21;349:g5128.

Nakashima T, Inoue K, Shiro-ozu A, Yoshinari M, Okamura K, Itoh M. Predominant T 3 synthesis in the metastatic thyroid carcinoma in a patient with T 3-toxicosis. Metabolism. 1981 Apr 30;30(4):327-30.

Paul SJ, Sisson JC. Thyrotoxicosis caused by thyroid cancer. Endocrinology and metabolism clinics of North America. 1990 Sep;19(3):593-612.

Russo D, Tumino S, Arturi F, Vigneri P, Grasso G, Pontecorvi A, Filetti S, Belfiore A. Detection of an Activating Mutation of the Thyrotropin Receptor in a Case of an Autonomously Hyperfunctioning Thyroid Insular Carcinoma. The Journal of Clinical Endocrinology & Metabolism. 1997 Mar 1;82(3):735-8.

Miyauchi A, Takamura Y, Ito Y, Miya A, Kobayashi K, Matsuzuka F, Amino N, Toyoda N, Nomura E, Nishikawa M. 3, 5, 3′-Triiodothyronine thyrotoxicosis due to increased conversion of administered levothyroxine in patients with massive metastatic follicular thyroid carcinoma. The Journal of Clinical Endocrinology & Metabolism. 2008 Jun;93(6):2239-42.

Kasagi K, Takeuchi R, Miyamoto S, et al. Rapid Control of T3 Thyrotoxicosis in Patients with Metastatic Follicular Thyroid Cancer Treated Metastatic thyroid cancer presenting as thyrotoxicosis: report of three cases. Clin Endocrinol (Oxf) 1994; 40:429.