Unusual suspects of secondary diabetes and growth retardation: Bartter and Gitelman syndrome
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Abstract
Bartter syndrome and Gitelman syndrome are rare autosomal recessive syndromes. In extremely rare cases, GS may diagnosed with growth retardation and diabetes mellitus. In this 3-case series, growth retardation was identified at 17-year follow-up of our dizygotic twin patients diagnosed with BS and glucose metabolism disorder was developed. Whereas, 3RD. patient diagnosed with GS in adulthood period developed diabetes mellitus after 8 years follow up. Chronic hypopotassemia has been shown to cause diabetes mellitus and growth retardation ın several articles. Potassium plays an important role in insulin, IGF-1 and growth hormone cycle. Herein, we aimed to draw attention to that, the presence of chronic hypopotassemia may precipitate to diseases such as growth retardation and diabetes mellitus over time.
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