Is There A Relationship Between The Umbilical Cord Coiling Index And Oxidative Stress Markers And SGA Fetuses? Coiling Index And Oxidative Stress

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Gul Nihal Buyuk
Zeynep Asli Oskovi Kaplan
Umit Yasemin Sert
Inci Halilzade
Salim Neselioglu
Ozcan Erel
Huseyin Levent Keskin


Objective: We aimed to investigate the relationship between umblical coiling index and thiol/disulfide balance in SGA newborns to compare with AGA newborns.

Material and Methods: Fetal umbilical cord serum samples were collected during labour and the thiol/disulfide homeostasis was measured. After birth, umbilical cords were collected and cord parameters were examined including, length, number of coils, umbilical cord index.

Results: Significant decrease in native thiol, total thiol, and a significant increase in disulfide, disulfide/native thiol ratio and disulfide/total thiol ratios were observed in the study group while native thiol/total thiol ratio levels of the two groups did not reach to a statistical significance.

Conclusion: The results of this study showed that SGA babies had altered thiol homeostasis in favor of oxidative stress.


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How to Cite
Buyuk, G. N., Kaplan, Z. A. O., Sert, U. Y., Halilzade, I., Neselioglu, S., Erel, O., & Keskin, H. L. (2021). Is There A Relationship Between The Umbilical Cord Coiling Index And Oxidative Stress Markers And SGA Fetuses?. Medical Science and Discovery, 8(5), 310-314.
Research Article


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