Helicobacter pylori and ischemic liver injury in heart failure: A new clinical association?

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Ali Muhtaroğlu
Furkan Ali Uygur
Selahattin Vural
Ahmet Cumhur Dülger


Objective: This study aimed to investigate the association between Helicobacter pylori (H. pylori) scolonisation and ischemic hepatitis in patients with heart failure.

Material Methods: A retrospective analysis was conducted on the medical records of 80 patients with heart failure who had undergone liver function tests. The patients were divided into two groups based on their liver function tests: those who developed ischemic hepatitis and those who did not. H. pylori scolonisation status was determined using serum immunoglobulin G antibody testing.

Results: Of the 80 patients, 47 (58.75%) had H. pylori colonisation. H. pylori scolonisation was more prevalent in the group of patients who developed ischemic hepatitis compared to those who did not (36.2% vs 63.8%, p<0.05). These findings suggest that H. pylori scolonisation may contribute to developing ischemic hepatitis in patients with heart failure.

Conclusion: This study provides evidence for an association between H. pylori scolonisation and ischemic hepatitis in patients with heart failure. The results suggest that H.pylori may contribute to this condition's development and that further research is needed to understand the mechanisms involved fully. These findings have important implications for healthcare professionals in managing heart failure and liver disease patients.


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How to Cite
Muhtaroğlu, A., Uygur, F. A. ., Vural, S. ., & Dülger, A. C. . (2023). Helicobacter pylori and ischemic liver injury in heart failure: A new clinical association?. Medical Science and Discovery, 10(7), 432–438. https://doi.org/10.36472/msd.v10i7.980
Research Article
Received 2023-06-20
Accepted 2023-06-27
Published 2023-07-01


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